LONATE

Description

L-Ornithine L-Aspartate – It is a pharmaceutical preparation containing two amino acids: ornithine and aspartate. It is widely prescribed to treat Liver Disease and nutritional deficiencies. L-Ornithine and L-Aspartate are used in managing liver-related disorders and reducing levels of a toxic chemical called ammonia in the blood. L-ornithine-L-aspartate belongs to the group of medicines called hepatoprotective agents. It works by protecting the liver from harmful chemical substances, such as free radicals, thus preventing liver damage. The injection is administered intravenously and given as a slow drip infusion.

L-Ornithine L-Aspartate injection is indicated for the treatment of various liver-related disorders, such as hepatic encephalopathy, acute and chronic hepatitis, fatty liver, jaundice, and liver cirrhosis by increasing the rate of energy production in liver cells.

F.C. Remedies is one of the most renowned Pharmaceutical companies, driving quality and innovation in every product and service, including high-quality L-Ornithine L-Aspartate 5 Gm Inj/10ml injection, which ensures safety and efficacy. It is marketed under the Brand name LONATE. Collaborate with F.C.Remedies for PCD Pharma Franchise Business Opportunities. 

What Is The Mode Of Action Of L-Ornithine L-Aspartate Injection?

Here’s a detailed discussion on the working mechanism of L-Ornithine L-Aspartate Injection, highlighted as follows: 

L-Ornithine L-Aspartate Injection mainly works due to its role in ammonia detoxification. 

1. Stimulation of the Urea Cycle 

• This step is led by the Ornithine amino acid, which helps the liver to remove harmful ammonia from the body by turning it into urea, which in turn is excreted via urine. The urea cycle is a metabolic pathway that takes place in the Liver. 
• By boosting the urea cycle, L-Ornithine L-Aspartate helps clear excess ammonia from the blood.

2. Promotion of Glutamine Synthesis

• Aspartate and ornithine stimulate the formation of glutamine from ammonia and glutamate, which mainly occurs in skeletal muscle and brain tissues. 
• This provides an additional non-urea pathway for ammonia detoxification. 

3. Improvement of Hepatic Energy Metabolism

Aspartate enters the Krebs cycle as oxaloacetate, supporting energy production in hepatocytes and other tissues. This may improve overall liver function. 

What is the Medical Benefit of Using L-Ornithine L-Aspartate Injection? 

Here’s a List of Medical Benefits of using L-Ornithine L-Aspartate Injection, listed as follows: 

1. It helps lower elevated ammonia levels in the bloodstream, which is important in managing hepatic encephalopathy and other liver-related conditions.
2. It helps to naturally detox the body by converting ammonia into urea, which is then excreted in urine.
3. It provides liver protective effects, especially in individuals with fatty liver disease or compromised liver function.
4. It is sometimes used in combination with other therapies for acute liver injury or alcoholic liver disease.
5. It also provides nutritional support, helping in protein metabolism.
6. It reduces the levels of ammonia in the body.

Possible Side Effects of Using L-Ornithine L-Aspartate Injection 

Along with its beneficial effects, a medicine may cause some unwanted side effects ranging from severe to common. Most of them do not require any medical attention. Consult your doctor if they persist or may cause any discomfort.

A List of Medical Benefits has been mentioned as follows: 

1. Injection Site Reaction
2. Swelling 
3. Rashes
4. Pain
5. Headache
6. Fatigue
7. Nausea

Safety and Precaution Measures 

Inform your healthcare provider about your recent or past Health issues. To ensure safe and effective use, the following precautions should be taken:

1. Regularly monitor your blood creatinine and blood/urine urea levels.
2. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.
3. Avoid taking this injection if you’re allergic to any of its ingredients.
4. Administration is usually intravenous (IV) under medical supervision.
5. It is usually safe when used in doses of up to 18 grams daily for up to 6 months. For further information, contact your healthcare provider. 

How to Store L-Ornithine L-Aspartate Injection?

Storage Instruction for this injection is mentioned as follows:

1. It should be stored at controlled room temperature (20°C to 25°C) 
2. Must keep away from light and moisture
3. Keep it out of children’s reach
4. Store in a dry place

Frequently Asked Questions (FAQ’s)

Q1. How is the injection administered?

This injection is given intravenously (IV) under the supervision of a healthcare professional. The dosage and duration depend on the patient’s condition and the doctor’s recommendation.

Q2. Can it be taken with other liver medications?

Yes, it is often prescribed alongside other liver-supportive medications. However, patients must inform their doctor about all medications they are currently taking to avoid potential interactions.

Q3. Is it safe for pregnant or breastfeeding women?

The safety of L-Ornithine L-Aspartate Injection in pregnancy and lactation has not been fully established. It should only be used if clearly prescribed by a doctor