Description
ESHODIN-D8
SILODOSIN 8 MG And DUTASTERIDE 0.5 MG CAPSULES
ESHODIN-D8 is a medicine formed by the formulation of two medicines, Silodosin and Dutasteride. This medicine is mostly used for the treatment of an enlarged prostate in men. In this condition, the patient faces problems in urinating, or caused by frequent urination. This medicine provides long-term relief from prostate size and progression. The normal dose for this medicine is once daily after a meal. while the medication period monitors blood pressure, prostate indicator, and side effects like dizziness, sexual changes, etc.
Indication for Silodosin 8 Mg And Dutasteride 0.5 Mg Capsules
ESHODIN-D8 is approved for adult men with symptomatic BPH, such as
Lower urinary tract symptoms (LUTS) such as weak urinary flow, straining to start the urinary flow, increasing frequency of urination, and nighttime urination
To reduce prostate size and prevent complications such as acute urinary retention (AUR) and surgical treatment.
Mechanism of action
The medicine is a formulation of two medicines, Silodosin 8 Mg And Dutasteride 0.5 Mg Capsule:
Silodosin uses the alpha‑A receptors in the prostate and bladder neck to relax smooth muscle and visits to improve flow and relieve symptoms such as urgency and hesitancy.
The dutasteride inhibits 5‑alpha reductase enzymes, reducing dihydrotestosterone (DHT) levels and reducing prostate size, achieving long-term symptom relief and reducing risk of progression.
Dosages and Administration
The dosages of Silodosin 8 Mg and Dutasteride 0.5 Mg Capsules must be prescribed by a doctor or healthcare provider and must follow their advice to avoid any unwanted conditions. Some of the recommended dosages are:
- It is used by adults only
- The normal dose is one capsule daily after a meal
Administration
- Swallow the capsule with water
- Regularly monitor the symptoms of improvement in prostate size, PSA levels, and side effects.
Possible side effects of Silodosin 8 Mg And Dutasteride 0.5 Mg Capsules
This medicine can show some side effects which are adapted by the body over time, but if they continue to persist them consult your doctor and seek medical assistance as soon as possible to avoid worsening of the condition. Some of the common side effects are
- Retrograde ejaculation
- Dizziness
- Low blood pressure
- Nasal congestion
- Diarrhoea
- Decreased libido
- Erectile dysfunction
- Headache
Precautions while using Silodosin 8 Mg And Dutasteride 0.5 Mg Capsules
While using Silodosin 8 Mg And Dutasteride 0.5 Mg Capsules , we must follow and keep in mind some precautions to avoid any unwanted conditions and to use the medicine to its full effectiveness. Some of the precautions that we must keep in check are:
- Hypersensitivity to any of the ingredients may cause renal impairment
- may cause low blood pressure be caution while lying/sitting
- may reduce libido and semen
- Dutasteride suppresses serum PSA levels by ~50%, masking signs of prostate cancer- the serum PSA should be adjusted and followed regularly (sterisonline.com).
- Surgery: Notify the ophthalmologist when having cataract or glaucoma surgery due to floppy iris syndrome
- Interactions: Silodosin is a liver metabolized drug (CYP3A4 and UGT2B7) – use caution with strong inhibitors. Dutasteride may interact with certain hormone therapies.
Storage instruction
- Keep it in a cool, dry place
- Keep it away from direct sunlight and moisture
- Keep away from children
- Check the expiry date before using
